Archive for the ‘diabetes mellitus type 2’ Category
Atorvastatin Is An Hmg-Coa Reductase Inhibitor
Atorvastatin Is An Hmg-Coa Reductase Inhibitor
Atorvastatin is an HMG-CoA reductase inhibitor, also known as a “statin. Atorvastatin should be used with extreme caution in CHILDREN younger than 10 years old and in those who have not reached puberty; safety and effectiveness in these children have not been confirmed. Atorvastatin is to be used only by the patient for whom it is prescribed. Atorvastatin will not be as effective in lowering your cholesterol if you do not follow a cholesterol-lowering diet plan. Atorvastatin is a cholesterol-lowering medication that blocks the production of cholesterol (a type of fat) in the body. Atorvastatin reduces low-density lipoprotein (LDL) cholesterol and total cholesterol in the blood. Atorvastatin is used to treat high cholesterol. Atorvastatin is also used to lower the risk of stroke, heart attack, or other heart complications in people with coronary heart disease or type 2 diabetes. Atorvastatin may also be used for other purposes not listed in this medication guide. Atorvastatin can make birth control pills less effective. Atorvastatin is not for use in children younger than 10 years of age. Atorvastatin can be taken with or without food. Atorvastatin is usually taken once a day. Atorvastatin is only part of a complete program of treatment that also includes diet, exercise, and weight control. Atorvastatin, a new 3-hydroxy-3methyl-glutaryl-coenzyme A (HMG-CoA) reductase inhibitor, has been approved by the US Food and Drug Administration for treatment of primary hypercholesterolaemia and mixed dyslipidaemia. Atorvastatin calcium: an addition to HMG-CoA reductase inhibitors. Atorvastatin is a highly effective statin (cholesterol-lowering drug) that lowers LDL cholesterol and triglyceride levels. Atorvastatin has also been shown to reduce the risk of heart attack or angina (chest pain) in people with coronary heart disease risk factors, such as hypertension, being age 55 years or older, smoking, low HDL cholesterol (“good” cholesterol) levels, or family history of early coronary heart disease. Atorvastatin is used to lower cholesterol and other lipids (fats) in the blood and may help prevent medical problems caused by cholesterol such as heart disease. Atorvastatin is not recommended for children under 10 years of age. Atorvastatin has also had a major cardiovascular events with regular dose simvastatin or atorvastatin in patients with known heart disease. Atorvastatin, an HMGCoA reductase inhibitor indicated for lowering cholesterol, is the
Effects Of Psyllium On Coronary Vascular Diseases
Effects Of Psyllium On Coronary Vascular Diseases
INTRODUCSSION
Extensive clinical and statistical studies have identified several factors that increase the risk of coronary heart disease (CHD) and heart attack. Major risk factors are those that research has shown significantly increase the risk of heart and blood vessel (cardiovascular) disease. Other factors are associated with increased risk of cardiovascular disease, but their significance and prevalence haven’t yet been precisely determined. They’re called contributing risk factors.1 The American Heart Association has identified several risk factors. Some of them can be modified, treated or controlled, and some can’t. The more risk factors you have, the greater your chance of developing coronary heart disease.2 Fats, like cholesterol and lipoproteins are major risk factors for CHD.3 Cholesterol in our body synthesizes many hormones, vitamin D, and the bile acids that help to digest fat. It takes only a small amount of cholesterol in the blood to meet these needs.4,10,12 If human body have too much cholesterol in bloodstream, the excess is deposited in arteries, including the coronary arteries, where it contributes to the narrowing and blockages that cause the signs and symptoms of heart disease.5Psyllium or Plantago ovata Forsk is an annual plant grown primarily in India, southern Europe and the United States. Psyllium is cultivated primarily for its use as a laxative or as a dietary fiber ingredient in foods, such as ready-to-eat cereals. It is also known as blond psyllium, Indian psyllium and plantain. Although the seed alone contains the bioactive mucilage polysaccharide, the refined psyllium seed husk, known as the Ispaghula husk, is the psyllium component principally used as the soluble fiber source for laxatives, ready-to-eat cereals and nutritional supplements.6,9 In specific doses, it lowers serum total cholesterol and LDL- Cholesterol remarkably.7 Psyllium husk fiber is a viscous, mostly water-soluble fiber prepared by mechanical removal of the husk from blonde psyllium seed (Plantago ovata). Early or uncontrolled studies suggested that psyllium improved glycemic and lipid control in individuals with type 2 diabetes.8,14 The mechanism of psyllium’s possible hypocholesterolemic activity is not fully understood. The bioactive agent of psyllium is a soluble, viscous xylan fiber. It is thought that this polysaccharide stimulates the conversion of cholesterol to bile acids and that it stimulates fecal
Ispaghol Fibers For Decreasing Hyperlipidemia
Ispaghol Fibers For Decreasing Hyperlipidemia
INTRODUCSSION
Coronary heart disease is usually caused by a condition called atherosclerosis, which occurs when fatty material and a substance called plaque build up on the walls of your arteries. This causes them to get narrow. As the coronary arteries narrow, blood flow to the heart can slow down or stop. This can cause chest pain (stable angina), shortness of breath, heart attack, and other symptoms.1Coronary heart disease (CHD) is the leading cause of death in the United States for men and women.2Many things increase risk for heart disease. One of the most common cause/risk is fats in the blood circulation.3Cholesterol in our body synthesizes many hormones, vitamin D, and the bile acids that help to digest fat. It takes only a small amount of cholesterol in the blood to meet these needs.4,10,12 If human body have too much cholesterol in bloodstream, the excess is deposited in arteries, including the coronary arteries, where it contributes to the narrowing and blockages that cause the signs and symptoms of heart disease.5Psyllium or Plantago ovata Forsk is an annual plant grown primarily in India, southern Europe and the United States. Psyllium is cultivated primarily for its use as a laxative or as a dietary fiber ingredient in foods, such as ready-to-eat cereals. It is also known as blond psyllium, Indian psyllium and plantain. Although the seed alone contains the bioactive mucilage polysaccharide, the refined psyllium seed husk, known as the Ispaghula husk, is the psyllium component principally used as the soluble fiber source for laxatives, ready-to-eat cereals and nutritional supplements.6,9 In specific doses, it lowers serum total cholesterol and LDL- Cholesterol remarkably.7 Psyllium husk fiber is a viscous, mostly water-soluble fiber prepared by mechanical removal of the husk from blonde psyllium seed (Plantago ovata). Early or uncontrolled studies suggested that psyllium improved glycemic and lipid control in individuals with type 2 diabetes.8,14 The mechanism of psyllium’s possible hypocholesterolemic activity is not fully understood. The bioactive agent of psyllium is a soluble, viscous xylan fiber. It is thought that this polysaccharide stimulates the conversion of cholesterol to bile acids and that it stimulates fecal excretion of bile acids. Psyllium may also decrease the intestinal absorption of cholesterol.9
PATIENTS&METHOD
Study was conducted in the